Lab-grown human mini-brains kept alive for a year by slicing them up

Mini-brain organoids showing cortex-like structures

Andras Lakatos/University of Cambridge

Miniature human brain-like structures have been grown in a dish for more than a year, much longer than has been achieved previously. The feat was accomplished by growing brain cells into a ball, then slicing it up so that oxygen and nutrients can reach all the cells, while allowing the structure to retain its internal tissue architecture.

The standard way to study tissues kept alive in the lab is to grow them as a single layer of cells in a dish. Then it was found that …

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